We see it everyday on the Tell-Lie-Vision screen...
Cyclosporine is an immunosuppressant drug that has been used since the early 1980's to prevent organ rejection after transplantation such as a liver transplant. It prevents rejection by inhibiting T Lymphocyte cells, specific cells of the immune system.
- High blood pressure.
- Increased hair growth. If this bothers your child, different methods of removing excess hair are available. Ask your doctor about the safest one for your child.
- Swollen or inflamed gums. Tell your coordinator if your child has swollen gums. Your child may require more dental care, such as increased brushing and flossing and more frequent dental visits. This side effect usually occurs with higher doses of cyclosporine and may improve as the dose is reduced.
- Numbness or tingling of the hands or feet. This side effect can be a sign that your child’s cyclosporine level is high. If your child’s medication is causing this side effect, the symptoms should improve as the medication dose is reduced.
- Other common side effects are tremors, restlessness, stomach upset, nausea, cramps, diarrhea, headache, and changes in blood sugar.
- Sinus drainage or runny nose. This effect should improve as the dose is reduced.
- Hot flashes or sweating. This effect may occur several hours after each dose and will improve as the dose is reduced.
- Elevated "kidney numbers." Your child’s creatinine and BUN will be monitored as part of irregular laboratory studies, to prevent and/or detect kidney damage. For this reason, it is important to always check with your coordinator before giving your child any new medications that could affect kidney function.
- Increased risk of infection
- Change in urination
- Sore throat
- Unusual bleeding or bruising
- Trouble breathing
- Blurred vision
- Stomach pain
- Hearing difficulty
- Chest pain
Common side effects of cyclosporine include:
Methotrexate may cause very serious, life-threatening side effects. You should only take methotrexate to treat cancer or certain other conditions that are very severe and that cannot be treated with other medications. Talk to your doctor about the risks of taking methotrexate for your condition.